Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207250 | 1.00 | LMNA (0.34) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31099096 | 1.00 | LMNA (0.34) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31099097 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31207273 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31207277 | 0.73 | TP53 (0.33) | LMNASMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL31207253 | 0.73 | EPHX2 (0.40) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31099103 | 0.73 | EPHX2 (0.40) | LMNASMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL24853451 | 0.70 | MEN1 (0.42) | ALDH1A1KDM4EMEN1KMT2ABACE1 | |
| SCHEMBL30318752 | 0.70 | MEN1 (0.42) | ALDH1A1KDM4EMEN1KMT2ABACE1 | |
| SCHEMBL31099050 | 0.70 | OPRM1 (0.34) | LMNAMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |