Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31099103 | 1.00 | EPHX2 (0.40) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31207273 | 0.88 | LMNA (0.40) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31099097 | 0.88 | LMNA (0.40) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31099093 | 0.79 | LMNA (0.39) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31207238 | 0.79 | LMNA (0.39) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL27229519 | 0.77 | MAPT (0.50) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL28525675 | 0.74 | LMNA (0.55) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31207250 | 0.73 | LMNA (0.34) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31207239 | 0.73 | LMNA (0.34) | EPHX2MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL31099096 | 0.73 | LMNA (0.34) | EPHX2MAPTLMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255412-A1 | SPIRO HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2024-12-19 | — | — | WO | disclosed |