Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109977 | 1.00 | GPR55 (0.54) | GPR55NR4A2RXRARXRBLMNA | |
| SCHEMBL3112231 | 0.88 | PPARA (0.50) | GPR55PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3112222 | 0.88 | PPARA (0.50) | GPR55PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3105403 | 0.87 | PPARG (0.50) | GPR55LMNAPPARDPPARAPPARG | |
| SCHEMBL3105387 | 0.87 | PPARG (0.50) | GPR55LMNAPPARDPPARAPPARG | |
| SCHEMBL3115382 | 0.86 | NR4A2 (0.54) | GPR55NR4A2RXRARXRBLMNA | |
| SCHEMBL3115372 | 0.86 | NR4A2 (0.54) | GPR55NR4A2RXRARXRBLMNA | |
| SCHEMBL3099593 | 0.84 | FFAR1 (0.47) | GPR55NR4A2LMNARECQLPPARD | |
| SCHEMBL3099584 | 0.84 | FFAR1 (0.47) | GPR55NR4A2LMNARECQLPPARD | |
| SCHEMBL3118799 | 0.84 | FFAR1 (0.48) | GPR55RXRARXRBPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | WYETH (US) | 2008-12-18 | — | — | US | claimed |
| US-20060247298-A1 | Substituted acetic acid derivatives | WYETH (US) | 2006-11-02 | — | — | US | claimed |
| US-7803835-B2 | Substituted acetic acid derivatives | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
| US-7411083-B2 | Substituted acetic acid derivatives | WYETH (US) | 2008-08-12 | — | — | US | disclosed |
| US-20060247298-A1 | Substituted acetic acid derivatives | WYETH (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | AADAC, ACACA, AANAT | GPR55 2239/4885NR4A2 2770/4885RXRA 589/4885 |
| US-20060247298-A1 | Substituted acetic acid derivatives | AADAC, ACACA, AANAT | GPR55 2239/4885NR4A2 2770/4885RXRA 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.