⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL5142032 | 0.87 | — | — | |
| Pyrrole SCHEMBL3807182 | 0.87 | — | — | |
| Pyrrole SCHEMBL311019 | 0.84 | — | — | |
| Pyrrole SCHEMBL31319 | 0.84 | — | — | |
| Pyrrole SCHEMBL27688372 | 0.84 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL28814397 | 0.84 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL27461767 | 0.84 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL711238 | 0.84 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL16344858 | 0.84 | ACHE (0.47) | — | |
| Pyrrole SCHEMBL28284015 | 0.84 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816823-A | Process for synthesizing chloroethylene by using mercury-free catalyst | 山东新龙节能环保设备有限公司 | 2021-12-21 | — | — | CN | claimed |
| JP-58159458-A | — | — | None | — | — | JP | disclosed |
| CN-115754113-A | Method for detecting content of catalyst tetrabutylammonium bromide in piracetam intermediate and finished product through high performance liquid chromatography | 东北制药集团股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-112022816-B | Piracetam tablet and preparation method thereof | 河北君临药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-113816823-A | Process for synthesizing chloroethylene by using mercury-free catalyst | 山东新龙节能环保设备有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112022816-A | Piracetam tablet and preparation method thereof | 河北君临药业有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-109400515-A | A kind of preparation method of the Piracetam based on continuous reaction | 嘉兴市秀洲区洪合镇中学 | 2019-03-01 | — | — | CN | disclosed |
| CN-108236608-A | Pharmaceutical composition of cannabidiol and vigabatrin and application thereof | 汉义生物科技（北京）有限公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-104693089-B | Continuous preparation process method of N-acetate pyrrolidone | 沈阳化工大学 | 2017-01-18 | — | — | CN | disclosed |
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |
| US-6730694-B1 | SPLA2 IS A RATE LIMITING ENZYME IN THE ARACHIDONIC ACID CASCADE WHICH HYDROLYZES MEMBRANE PHOSPHOLIPIDS; TREATMENT OF SEPSIS OR RHEUMATOID ARTHRITIS | ELI LILLY AND COMPANY | 2004-05-04 | — | — | US | disclosed |
| EP-1307461-A2 | SUBSTITUTED PYRROLE COMPOUNDS AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012249-A2 | SUBSTITUTED PYRROLE COMPOUNDS AND THEIR USE AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| CN-1074933-C | Anti-stress, anti-impairment and anti-aging drug and process for manufacturing thereof | RIGA D (RO) | 2001-11-21 | — | — | CN | disclosed |
| JP-S58159458-A | PYRROLE ACETIC ACID AMIDE, MANUFACTURE AND MEDICINE | SIGMA TAU IND FARMACEUTI | 1983-09-21 | — | — | JP | disclosed |