Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105897 | 0.90 | RXRA (0.40) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL31105893 | 0.89 | LCK (0.41) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL31105927 | 0.80 | HCK (0.44) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL19949097 | 0.77 | RXRA (0.43) | RXRARXRBRXRGDGAT2CYP4F2 | |
| SCHEMBL31105912 | 0.77 | MAPK14 (0.50) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL31105920 | 0.77 | LCK (0.37) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL31705188 | 0.76 | LCK (0.52) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL21195976 | 0.75 | RXRA (0.46) | RXRARXRBRXRGDGAT2CYP4F2 | |
| SCHEMBL31106108 | 0.75 | CYP4F2 (0.37) | LCKMAPK14RXRARXRBRXRG | |
| SCHEMBL31106070 | 0.74 | LCK (0.43) | LCKRXRARXRBRXRGCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |