Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 8/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | HCK | P08631 | 4/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | SIK1 | P57059 | 1/20 | 0.31 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.31 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106170 | 0.94 | KRAS (0.36) | KRASLCKMAPK14HCKABL1 | |
| SCHEMBL31106079 | 0.85 | LCK (0.38) | LCKMAPK14HCKABL1SRC | |
| SCHEMBL31105882 | 0.84 | LCK (0.38) | LCKMAPK14HCKSRCMAPK13 | |
| SCHEMBL31105877 | 0.82 | LCK (0.37) | KRASLCKMAPK14HCKABL1 | |
| SCHEMBL31105878 | 0.81 | HCK (0.39) | LCKMAPK14HCKABL1SIK1 | |
| SCHEMBL31106084 | 0.81 | LCK (0.36) | KRASLCKMAPK14HCKABL1 | |
| SCHEMBL31105995 | 0.81 | LCK (0.37) | LCKMAPK14HCKABL1SRC | |
| SCHEMBL31106147 | 0.78 | HCK (0.39) | LCKMAPK14HCKABL1SRC | |
| SCHEMBL31105951 | 0.78 | LCK (0.43) | LCKMAPK14HCKABL1SRC | |
| SCHEMBL31105897 | 0.77 | RXRA (0.40) | LCKMAPK14HCKSRCMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024184520-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-09-12 | — | — | WO | disclosed |