Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylic Acid SCHEMBL11170096 | 0.74 | KIF11 (0.41) | KIF11PARP10L3MBTL1MAPTMEN1 | |
| Ethylenediamine SCHEMBL28984464 | 0.71 | KIF11 (0.40) | KIF11CES1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7593319 | 0.70 | CES1 (0.65) | CES1PARP10L3MBTL1MAPTMEN1 | |
| SCHEMBL11514626 | 0.69 | CES1 (0.44) | CES1ALOX15L3MBTL1MAPTRAB9A | |
| SCHEMBL25353899 | 0.68 | SSTR4 (0.40) | CES1LTA4HALOX15 | |
| SCHEMBL30045985 | 0.68 | CA2 (0.40) | PARP10ALOX15L3MBTL1MAPTPPARG | |
| SCHEMBL7033474 | 0.68 | PPARA (0.47) | L3MBTL1MAPTPPARGMEN1KMT2A | |
| SCHEMBL27520136 | 0.68 | PPARG (0.47) | ALOX15L3MBTL1MAPTRAB9APPARG | |
| Ethylenediamine SCHEMBL29214558 | 0.68 | TAAR1 (0.42) | TAAR1PARP10MTNR1AMTNR1BPPARG | |
| SCHEMBL28905388 | 0.67 | CES1 (0.59) | CES1SMN1; SMN2MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181788-B | Glass cleaning agent and preparation method and application thereof | 万津实业(赤壁)有限公司 | 2024-07-19 | — | — | CN | claimed |