SCHEMBL30045985

SCHEMBL30045985

O=C([O-])C(Cl)(Cl)Oc1ccccc1.[Na+]

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 1/20 0.40
CA4 known ✓ P22748 1/20 0.40
PPARG known ✓ P37231 2/20 0.35
CYP1A2 P05177 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.36
PPARA Q07869 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
ATM Q13315 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
SRC P12931 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PARP10 Q53GL7 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692135 0.81 CYP1A2 (0.46) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL8584192 0.81 CYP1A2 (0.41) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL27597867 0.81 PPARA (0.41) CA2CA4CYP1A2MEN1KMT2A
Phosphine SCHEMBL27522539 0.79 CYP1A2 (0.45) CYP1A2MEN1KMT2AALDH1A1ALOX15
Ammonia Solution, Strong SCHEMBL27869910 0.79 CYP1A2 (0.45) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL11851064 0.79 CYP1A2 (0.40) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL28107544 0.79 CYP1A2 (0.45) CYP1A2MEN1KMT2AALDH1A1ALOX15
Water SCHEMBL28856009 0.79 CYP1A2 (0.45) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL28219394 0.79 CYP1A2 (0.45) CYP1A2MEN1KMT2AALDH1A1ALOX15
SCHEMBL6003069 0.78 LTA4H (0.41) CA2CA4CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583879-A Production process and system of high-concentration 2,4-sodium dropwise salt 安徽兴隆化工有限公司 2023-01-10 CN claimed
CN-114041467-B Preparation method of super absorbent resin for inhibiting weed growth, sterilizing and promoting crop growth 潍坊科技学院 2023-07-28 CN disclosed
CN-115583879-A Production process and system of high-concentration 2,4-sodium dropwise salt 安徽兴隆化工有限公司 2023-01-10 CN disclosed
CN-113115772-B Slow-release pesticide with expanded perlite as carrier and preparation method thereof 仲恺农业工程学院 2022-12-20 CN disclosed
CN-115460925-A Herbicidal mentha plant extract compositions and methods of use thereof 哈普生物除草剂解决方案公司 2022-12-09 CN disclosed