Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440762 | 0.80 | CES1 (0.60) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL935810 | 0.80 | CES1 (0.60) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL20535074 | 0.73 | TGM2 (0.42) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL31107461 | 0.69 | CES1 (0.43) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL15490689 | 0.69 | GSK3B (0.71) | LRRK2DYRK1BALDH1A1GSK3BPARP1 | |
| SCHEMBL13312397 | 0.68 | GSK3B (0.41) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL22300869 | 0.67 | MAOA (0.46) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL988494 | 0.67 | LRRK2 (0.61) | CDK5LRRK2DYRK1BTGM2ALDH1A1 | |
| SCHEMBL29479580 | 0.67 | LRRK2 (0.61) | CDK5LRRK2DYRK1BTGM2ALDH1A1 | |
| SCHEMBL7423435 | 0.67 | CA1 (0.43) | PIM1CSNK1A1CDK5ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440081-A | Four-ring condensed skeleton compound containing indoline unit and synthesis method thereof | 西南交通大学 | 2024-08-06 | — | — | CN | claimed |
| CN-118440081-A | Four-ring condensed skeleton compound containing indoline unit and synthesis method thereof | 西南交通大学 | 2024-08-06 | — | — | CN | disclosed |