Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564532 | 1.00 | KDM4E (0.50) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL20565627 | 0.82 | KDM4E (0.48) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL31111338 | 0.82 | KDM4E (0.48) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL20565594 | 0.80 | ALDH1A1 (0.56) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL17985912 | 0.77 | RHOA (0.54) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL7140165 | 0.77 | NOTUM (0.66) | USP2NPSR1NOTUMLMNAHTT | |
| SCHEMBL31381239 | 0.75 | NEK2 (0.49) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL20565681 | 0.75 | KDM4E (0.56) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL20565233 | 0.74 | KDM4E (0.55) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL31381279 | 0.73 | LMNA (0.54) | KDM4EHPGDNEK2CYP2C19NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285572-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264073-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-110913858-B | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2024-09-24 | — | — | CN | disclosed |