Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061138 | 1.00 | MAPT (0.54) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL22131607 | 0.86 | ALDH1A1 (0.50) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL12434067 | 0.81 | OXTR (0.55) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL19657715 | 0.80 | S1PR1 (0.38) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL2060626 | 0.79 | MAPT (0.44) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL17927769 | 0.79 | FABP6 (0.49) | MAPTS1PR1S1PR3RIPK1ACHE | |
| SCHEMBL20565297 | 0.79 | PNMT (0.53) | S1PR1S1PR3RIPK1ACHEPNMT | |
| SCHEMBL2983125 | 0.79 | PNMT (0.53) | MAPTALDH1A1GAAHSD17B10CD274 | |
| SCHEMBL30174754 | 0.79 | PNMT (0.53) | S1PR1S1PR3RIPK1ACHEPNMT | |
| SCHEMBL30644265 | 0.79 | PNMT (0.53) | MAPTALDH1A1GAAHSD17B10CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110913858-B | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2024-09-24 | — | — | CN | disclosed |