Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27899369 | 0.93 | DAO (0.45) | ALDH1A1HTTPLA2G4BMAPTTSHR | |
| Benzoic Acid SCHEMBL27623024 | 0.88 | DAO (0.47) | ALDH1A1HTTPLA2G4BMAPTTSHR | |
| Terephthalic Acid SCHEMBL16227375 | 0.88 | PLA2G4B (0.54) | ALDH1A1PLA2G4BMAPTTP53TSHR | |
| 3-Octanol SCHEMBL7446463 | 0.81 | PLA2G4B (0.48) | PLA2G4BTP53TSHRRARB | |
| 4-Methylbenzoic Acid SCHEMBL1786534 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HTTPLA2G4BMAPTTP53 | |
| Terephthalic Acid SCHEMBL27678502 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTPLA2G4BMAPTTP53 | |
| SCHEMBL19970630 | 0.81 | PLA2G4B (0.66) | HTTPLA2G4BTP53TSHRRARB | |
| Benzoic Acid SCHEMBL5081312 | 0.81 | TSHR (0.50) | ALDH1A1HTTPLA2G4BMAPTTP53 | |
| Benzoic Acid SCHEMBL1073076 | 0.81 | TSHR (0.50) | ALDH1A1HTTPLA2G4BMAPTTP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL1081919 | 0.80 | TSHR (0.55) | ALDH1A1HTTMAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024181964-A1 | SOLVENT-BASED INKJET INKS | KAO CORPORATION (JP) | 2024-09-06 | — | — | WO | disclosed |