Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1073076 | 1.00 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28058177 | 0.95 | DAO (0.45) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9853337 | 0.94 | DAO (0.44) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27623024 | 0.90 | DAO (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27899369 | 0.88 | DAO (0.45) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27642143 | 0.88 | TRPA1 (0.43) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27522404 | 0.88 | DAO (0.48) | TSHRDAONAPRTCES2CES1 | |
| 4-Methylbenzoic Acid SCHEMBL1786534 | 0.86 | ALDH1A1 (0.57) | TSHRCES2CES1SRD5A2ALDH1A1 | |
| Cinnamic Acid SCHEMBL14053438 | 0.86 | HDAC3 (0.50) | ALDH1A1RAB9AHTTLMNAPKM | |
| Dodecanoate SCHEMBL27657732 | 0.86 | FFAR4 (0.51) | TSHRCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104558284-B | Catalytic component for olefinic polymerization and preparation method thereof and the catalyst for olefinic polymerization and application | 中国石油化工股份有限公司 | 2017-09-29 | — | — | CN | claimed |
| EP-1970388-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION OR COPOLYMERIZATION,PREPARATION METHOD THEREOF, CATALYST CONTAINING SAID CATALYST COMPONENT AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2008-09-17 | — | — | EP | claimed |
| US-7388060-B2 | Catalyst component for olefin (co)polymerization, preparation thereof, a catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | claimed |
| US-20070155616-A1 | Catalyst component for olefin (Co)polymerization, preparation thereof, a catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2007-07-05 | — | — | US | claimed |
| WO-2024242252-A1 | SEMI-SOLID OR SOLID BODY FOR ELECTRONIC CIGARETTE AND METHOD FOR MANUFACTURING SAME | 주식회사 이엠텍 | 2024-11-28 | — | — | WO | disclosed |
| CN-106687513-B | Polymer compositions with improved noise suppression | 伊士曼化工公司 | 2020-02-07 | — | — | CN | disclosed |
| EP-3194483-B1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEM CO (US) | 2018-12-19 | — | — | EP | disclosed |
| US-10077352-B2 | Polymeric compositions with improved noise suppression | EASTMAN CHEMICAL COMPANY (US) | 2018-09-18 | — | — | US | disclosed |
| EP-3194484-B1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEM CO (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20160075855-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-17 | — | — | US | disclosed |
| US-20160075857-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-17 | — | — | US | disclosed |
| US-20160075856-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-17 | — | — | US | disclosed |
| US-20160075858-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | EASTMAN CHEMICAL COMPANY (US) | 2016-03-17 | — | — | US | disclosed |
| EP-1970388-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION OR COPOLYMERIZATION,PREPARATION METHOD THEREOF, CATALYST CONTAINING SAID CATALYST COMPONENT AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2008-09-17 | — | — | EP | disclosed |
| US-7388060-B2 | Catalyst component for olefin (co)polymerization, preparation thereof, a catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-20070155616-A1 | Catalyst component for olefin (Co)polymerization, preparation thereof, a catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2007-07-05 | — | — | US | disclosed |
| CN-1834118-A | Catalyst compsns. for olefin polymerization and catalyst thereof | CHINA PETROCHEMICAL CORP (CN) | 2006-09-20 | — | — | CN | disclosed |
| CN-1436237-A | Nucleotide sequences involved in increasing or decreasing ovulation rate in mammals | AGRES LTD (NZ) | 2003-08-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075858-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | LRBA, FARSB, PUF60 | TSHR 4848/4885DAO 4445/4885NAPRT 1811/4885 |
| US-10077352-B2 | Polymeric compositions with improved noise suppression | LRBA, FARSB, PUF60 | TSHR 4848/4885DAO 4445/4885NAPRT 1811/4885 |
| US-20160075857-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | LRBA, FARSB, PUF60 | TSHR 4848/4885DAO 4445/4885NAPRT 1811/4885 |
| US-20160075855-A1 | POLYMERIC COMPOSITIONS WITH IMPROVED NOISE SUPPRESSION | LRBA, FARSB, PUF60 | TSHR 4848/4885DAO 4445/4885NAPRT 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.