4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL1786534

CCC(O)CCO.Cc1ccc(C(=O)O)cc1.Cc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SRD5A2 P31213 2/20 0.52
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
LMNA P02545 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL5081312 0.86 TSHR (0.50) ALDH1A1SMN1; SMN2SRD5A2HTTMAPT
Benzoic Acid SCHEMBL1073076 0.86 TSHR (0.50) ALDH1A1SMN1; SMN2SRD5A2HTTMAPT
SCHEMBL1070904 0.85 RXRA (0.43) ALDH1A1SMN1; SMN2HTTMAPTTP53
4-Chloro-Benzoic Acid SCHEMBL1081919 0.85 TSHR (0.55) ALDH1A1SMN1; SMN2SRD5A2HTTMAPT
4-Methylbenzoic Acid SCHEMBL14715179 0.84 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2SRD5A2HTTMAPT
SCHEMBL1073369 0.83 SRD5A2 (0.56) SMN1; SMN2SRD5A2HTTMAPTKMT2A
Benzoic Acid SCHEMBL28058177 0.82 DAO (0.45) ALDH1A1SMN1; SMN2SRD5A2HTTMAPT
Terephthalic Acid SCHEMBL31111408 0.81 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2HTTMAPTTP53
Benzoic Acid SCHEMBL9853337 0.81 DAO (0.44) ALDH1A1SRD5A2HTTMAPTTSHR
4-Methylbenzoic Acid SCHEMBL207185 0.80 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-03-26 US disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
US-20170101486-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, A CATALYST COMPONENT AND A CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-04-13 US disclosed
US-9499569-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-11-22 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US disclosed
EP-2454290-B1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL (CN) 2014-04-16 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US disclosed
US-20120184694-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, A CATALYST COMPONENT AND A CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-07-19 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
US-20100273641-A1 Self-Limiting Catalyst Composition with Non-Phthalate Internal Donor W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom MSMO1, SCO2, RTF1 ALDH1A1 3333/4885SMN1; SMN2 3765/4885SRD5A2 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.