Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275363 | 1.00 | ADORA2A (0.59) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL23299959 | 0.85 | ADORA2A (0.63) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL29762385 | 0.84 | ADORA2A (0.59) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL23274769 | 0.84 | ADORA2A (0.59) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL23854549 | 0.83 | KIF18A (0.52) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL24766030 | 0.79 | KMT2A (0.47) | ADORA2AADORA1KMT2ATHRBMEN1 | |
| SCHEMBL29762583 | 0.78 | MTOR (0.47) | KMT2ATHRBMEN1KDM4EALDH1A1 | |
| SCHEMBL23275235 | 0.78 | MTOR (0.47) | KMT2ATHRBMEN1KDM4EALDH1A1 | |
| SCHEMBL28602296 | 0.78 | RAB9A (0.54) | THRBKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL23299970 | 0.78 | KMT2A (0.52) | KMT2AMEN1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845711-B | Inhibitors of RAF kinase | 皮埃尔法布雷医药公司 | 2024-10-01 | — | — | CN | disclosed |