SCHEMBL31111478

SCHEMBL31111478

O=C(O)Nc1ccccc1F

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.72
NPC1 O15118 8/20 0.72
SMN1; SMN2 Q16637 5/20 0.72
ALDH1A1 P00352 4/20 0.61
HTT P42858 3/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
EGFR P00533 1/20 0.58
MMP1 P03956 1/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
POLB P06746 1/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 3/20 0.55
MAPT P10636 1/20 0.55
NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703904 1.00 RAB9A (0.72) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL6850971 0.84 RAB9A (0.75) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL30851501 0.84 RAB9A (1.00) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL11202950 0.84 RAB9A (1.00) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL3904710 0.84 RAB9A (0.52) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL29519193 0.83 SMN1; SMN2 (0.54) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL1226530 0.83 SMN1; SMN2 (0.54) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL440095 0.83 RAB9A (0.67) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL2089517 0.83 KMT2A (0.52) RAB9ANPC1SMN1; SMN2ALDH1A1HTT
SCHEMBL157188 0.82 RAB9A (0.72) RAB9ANPC1SMN1; SMN2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673442-A1 PHOTOSWITCHABLE COMPOUNDS AND AFFINITY LIGANDS, AND THEIR USE FOR THE OPTICAL CONTROL OF AFFINITY MATRICES AFC Innovations GmbH (DE) 2026-01-07 EP disclosed
WO-2024227104-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY NURIX THERAPEUTICS, INC. (US) 2024-10-31 WO disclosed
WO-2024180254-A1 PHOTOSWITCHABLE COMPOUNDS AND AFFINITY LIGANDS, AND THEIR USE FOR THE OPTICAL CONTROL OF AFFINITY MATRICES AFC INNOVATIONS GMBH (DE) 2024-09-06 WO disclosed