Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31111744 | 0.81 | PDE10A (0.33) | PDE10AMAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL31074565 | 0.81 | MAPK14 (0.34) | PDE10AMAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL29280467 | 0.77 | BRAF (0.44) | PDE10AMAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL26453172 | 0.76 | S1PR1 (0.35) | PDE10A | |
| SCHEMBL1847543 | 0.76 | BRAF (0.39) | PDE10AMAPK14 | |
| SCHEMBL26453167 | 0.75 | PTGIR (0.37) | PDE10A | |
| SCHEMBL31111573 | 0.74 | DGAT1 (0.37) | PDE10AMAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL1846834 | 0.74 | BRAF (0.37) | PDE10AMAPK14 | |
| Lithium Ion SCHEMBL1846833 | 0.73 | BRAF (0.37) | PDE10AMAPK14 | |
| SCHEMBL574873 | 0.73 | BRAF (0.42) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |