SCHEMBL31116

SCHEMBL31116

O=C1CC=Nc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
CDC25B P30305 2/20 0.35
CES1 P23141 3/20 0.34
BCHE P06276 2/20 0.34
MAOA P21397 4/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
MAOB P27338 2/20 0.33
LMNA P02545 2/20 0.33
S100A4 P26447 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP2A6 P11509 1/20 0.33
CES2 O00748 1/20 0.33
APAF1 O14727 1/20 0.33
TERT O14746 1/20 0.33
NPC1 O15118 1/20 0.33
PLIN1 O60240 1/20 0.33
TDP2 O95551 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3646726 0.98 MEN1 (0.33) MEN1KMT2ACDC25BCES1BCHE
Hydrochloric Acid SCHEMBL3397921 0.98 MEN1 (0.33) MEN1KMT2ACDC25BCES1BCHE
Fluoride SCHEMBL4741377 0.98 MEN1 (0.33) MEN1KMT2ACDC25BCES1BCHE
Iodide SCHEMBL7508635 0.98 S100A4 (0.34) MEN1KMT2ACDC25BCES1BCHE
Fumaric Acid SCHEMBL4611826 0.86 KDM4E (0.39) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL3590698 0.76 NOTUM (0.33) MEN1KMT2ACDC25BCES1BCHE
SCHEMBL17994855 0.74 ACHE (0.31)
SCHEMBL17337947 0.74 MAOA (0.32) MAOAMAOB
SCHEMBL4554791 0.74 MAOA (0.38) CDC25BMAOAMAPTKDM4EMAOB
SCHEMBL398908 0.74 IDO1 (0.32) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2932 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
US-20260014137-A1 METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS WAYNE STATE UNIVERSITY (US) 2026-01-15 US claimed
US-20250332117-A1 Thin Films with Peroxides and Uses Thereof Silverpeutics, Inc. (US) 2025-10-30 US claimed
CN-116120227-B Preparation method of 4-quinolone derivative 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2025-02-28 CN claimed
CN-119306697-A 4-Quinolinone derivative and preparation method and application thereof 山东大学 2025-01-14 CN claimed
CN-119013279-A Substituted tricyclic compounds as PARP inhibitors and uses thereof 上海瑛派药业有限公司 2024-11-22 CN claimed
CN-118598330-A Application of reduced iron powder in treatment of quinolone-containing wastewater and method for treating quinolone-containing wastewater 广东工业大学 2024-09-06 CN claimed
EP-4392425-A1 SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND USE THEREOF Impact Therapeutics (Shanghai), Inc. (CN) 2024-07-03 EP claimed
CN-118271393-A FAP-targeted dimeric compound, probe and application thereof 中国药科大学 2024-07-02 CN claimed
US-12005253-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2024-06-11 US claimed
EP-0104959-B1 4-QUINOLONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1987-01-21 EP claimed
EP-0206616-A2 Quinolones having antihypertensive activity The Boots Company PLC (GB) 1986-12-30 EP claimed
EP-0090769-B1 PROCESS FOR THE PREPARATION OF 1,2,5,6-TETRAHYDRO-4H-PYRROLO(3,2,1-IJ)-QUINOLIN-4-ONE AND 5-HALO-1,2,3-(1,2,DIHYDROPYRROLO)-4-QUINOLONE INTERMEDIATES CIBA-GEIGY AG (CH) 1986-08-20 EP claimed
US-4595755-A 5-halo-1,2,3-(1,2-dihydropyrrolo)-4-quinolones CIBA-GEIGY CORPORATION (US) 1986-06-17 US claimed
US-4518685-A BLOCKED AGENT FOR STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1985-05-21 US claimed
US-4508902-A OXIDATION OF 1,2,3,4-TETRAHYDROQUINOLINE-4-ONES RHONE-POULENC SANTE (FR) 1985-04-02 US claimed
EP-0125523-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-11-21 EP claimed
US-4421920-A AMINATION, AROMATIZATION, RUTHENIUM CATALYST RHONE-POULENC SANTE (FR) 1983-12-20 US claimed
EP-0000203-B1 1-ETHYL-7-CHLORO-6-FLUORO-4-QUINOLONE-3-CARBOXYLIC ACID, ITS PREPARATION AND APPLICATION AS PLANT BACTERICIDE CIBA-GEIGY AG (CH) 1981-07-01 EP claimed
US-3995040-A Cyclopenteno-3-carboxyl-4-quinolone derivatives and their bacteriostatic compositions BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-11-30 US claimed