SCHEMBL31116611

SCHEMBL31116611

COc1cccc2c(OC)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA7 P43166 3/20 0.61
CA9 Q16790 3/20 0.61
CA12 O43570 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA4 P22748 1/20 0.61
IDO1 P14902 1/20 0.58
EP300 Q09472 1/20 0.56
KAT8 Q9H7Z6 1/20 0.56
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 3/20 0.52
TP53 P04637 2/20 0.52
KDM4E B2RXH2 2/20 0.52
LMNA P02545 2/20 0.52
HPGD P15428 2/20 0.52
MAPT P10636 2/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357145 1.00 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL12473426 0.94 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL29380721 0.88 IDO1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL419307 0.88 IDO1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL9005269 0.87 CYP2A6 (0.62) CA1CA2CA7CA9CA12
SCHEMBL2987997 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL1402385 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL1807579 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL485125 0.85 IDO1 (0.76) CA1CA2CA7CA9CA12
SCHEMBL1402324 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878404-A Naphthoquinone-naphthol derivative derived from marine fungi as well as preparation method and application thereof 上海海洋大学 2024-11-01 CN claimed
CN-122079752-A Preparation method of 1,4,5, 8-tetramethoxynaphthalene compound containing shikonin characteristic side chain and 6-fluoro derivative thereof 2026-05-26 CN disclosed
CN-118878404-A Naphthoquinone-naphthol derivative derived from marine fungi as well as preparation method and application thereof 上海海洋大学 2024-11-01 CN disclosed
CN-118689035-A Hard mask composition, hard mask layer and method of forming pattern 三星SDI株式会社 2024-09-24 CN disclosed