Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594856 | 0.86 | IDO1 (0.57) | IDO1CA1CA2CA12CA7 | |
| SCHEMBL31116611 | 0.85 | CA1 (0.61) | IDO1CA1CA2CA12CA7 | |
| SCHEMBL357145 | 0.85 | CA1 (0.61) | IDO1CA1CA2CA12CA7 | |
| SCHEMBL12473426 | 0.80 | CA1 (0.55) | IDO1CA1CA2CA12CA7 | |
| SCHEMBL30608894 | 0.77 | NOS1 (0.44) | IDO1HPGDALDH1A1LMNATP53 | |
| SCHEMBL1269977 | 0.77 | NOS1 (0.44) | IDO1HPGDALDH1A1LMNATP53 | |
| SCHEMBL7285232 | 0.76 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4136425 | 0.76 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL245025 | 0.75 | — | — | |
| SCHEMBL29463736 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745579-B2 | Extrudable poly(propylene) compositions | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200071557-A1 | EXTRUDABLE POLY(PROPYLENE) COMPOSITIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-03-05 | — | — | US | disclosed |
| US-10556990-B2 | Porous/nanoporous PHT | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-02-11 | — | — | US | disclosed |
| US-20190211152-A1 | POROUS/NANOPOROUS PHT | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-07-11 | — | — | US | disclosed |
| US-10328415-B2 | Methods and apparatus for controlling metals in liquids | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-06-25 | — | — | US | disclosed |
| US-10329380-B2 | Lactide-derived polymers with improved materials properties via polyhexahydrotriazines (PHT) reaction | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-06-25 | — | — | US | disclosed |
| US-9931409-B2 | Methods and materials for therapeutic delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-9890248-B2 | Porous/nanoporous PHT | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170173170-A1 | METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-06-22 | — | — | US | disclosed |
| US-20170145143-A1 | SYNTHESIS OF DYNAMIC COVALENT 3D CONSTRUCTS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-05-25 | — | — | US | disclosed |
| US-9598608-B2 | Soluble, processable polyhemiaminals and polyhexahydrotriazines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-03-21 | — | — | US | disclosed |
| US-20170066662-A1 | METHODS AND APPARATUS FOR CONTROLLING METALS IN LIQUIDS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-03-09 | — | — | US | disclosed |
| US-8278442-B2 | Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders | PROSIDION LIMITED (GB) | 2012-10-02 | — | — | US | disclosed |
| US-20100173886-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-07-08 | — | — | US | disclosed |
| EP-2152671-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2010-02-17 | — | — | EP | disclosed |
| WO-2009010947-A1 | NEW DONOR-ACCEPTOR-DONOR-ACCEPTOR COMPOUNDS FOR NON-LINEAR APPLICATIONS | MEMPILE INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2008142454-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008142454-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173886-A1 | BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | OPRM1, OPRK1, OPRD1 | IDO1 599/4885CA1 4871/4885CA2 4563/4885 |
| US-20170173170-A1 | METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY | PAICS, PHPT1, MAPT | IDO1 2176/4885CA1 42/4885CA2 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.