SCHEMBL357145

SCHEMBL357145

COc1cccc2c(OC)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA7 P43166 3/20 0.61
CA9 Q16790 3/20 0.61
CA12 O43570 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA4 P22748 1/20 0.61
IDO1 P14902 1/20 0.58
EP300 Q09472 1/20 0.56
KAT8 Q9H7Z6 1/20 0.56
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 3/20 0.52
TP53 P04637 2/20 0.52
KDM4E B2RXH2 2/20 0.52
LMNA P02545 2/20 0.52
HPGD P15428 2/20 0.52
MAPT P10636 2/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31116611 1.00 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL12473426 0.94 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL29380721 0.88 IDO1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL419307 0.88 IDO1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL9005269 0.87 CYP2A6 (0.62) CA1CA2CA7CA9CA12
SCHEMBL2987997 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL1402385 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL1807579 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL485125 0.85 IDO1 (0.76) CA1CA2CA7CA9CA12
SCHEMBL1402324 0.85 IDO1 (0.47) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110143858-B Polysubstituted benzene compound with bioactivity and preparation method and application thereof 华南理工大学 2022-04-29 CN claimed
EP-3753931-A1 MULTI-SUBSTITUTED BENZENE COMPOUND HAVING BIOLOGICAL ACTIVITY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Genifarm Laboratories Inc (CN) 2020-12-23 EP claimed
US-20200361893-A1 POLYSUBSTITUTED BENZENE, PREPARATION METHOD THEREOF, AND METHOD OF USING THE SAME SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2020-11-19 US claimed
CN-106967023-B A kind of preparation method of β -2,6- dideoxy sugar aryl-C- glucosides 华东师范大学 2019-09-10 CN claimed
CN-110143858-A Biologically active Multi substituted benzenes compound and its preparation method and application 华南理工大学 2019-08-20 CN claimed
WO-2019153954-A1 MULTI-SUBSTITUTED BENZENE COMPOUND HAVING BIOLOGICAL ACTIVITY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 广州自远生物科技有限公司 2019-08-15 WO claimed
CN-108530242-A A kind of direct nitration method of electron rich aromatic hydrocarbons 中国科学院青岛生物能源与过程研究所 2018-09-14 CN claimed
CN-106967023-A A kind of preparation method of the sugared aryl C glucosides of the dideoxies of β 2,6 华东师范大学 2017-07-21 CN claimed
EP-0036502-B1 2-ALKYL-5-HYDROXY-1,4-NAPHTHOQUINONES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS ZYMA GMBH (DE) 1983-10-19 EP claimed
EP-0036502-A1 2-Alkyl-5-hydroxy-1,4-naphthoquinones, process for their manufacture and pharmaceutical preparations containing these compounds ZYMA GMBH (DE) 1981-09-30 EP claimed
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE CONWAY DAVID JONATHAN (US) 2026-01-22 US disclosed
WO-2025230237-A1 MANUFACTURING METHOD FOR INTERMEDIATE COMPOUND FOR SHIKONIN SYNTHESIS 주식회사 그라스메디 2025-11-06 WO disclosed
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed
US-20230152695-A1 RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
US-20230152695-A1 RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
US-4327022-A Heterocyclic alkyl naphthols STERLING DRUG INC. (US) 1982-04-27 US disclosed
EP-0036502-A1 2-Alkyl-5-hydroxy-1,4-naphthoquinones, process for their manufacture and pharmaceutical preparations containing these compounds ZYMA GMBH (DE) 1981-09-30 EP disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed
US-4207224-A Plastics composition CIBA-GEIGY AG (CH) 1980-06-10 US disclosed
US-4169108-A 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols STERLING DRUG INC. (US) 1979-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE TRPV3, VDR, TRPC3 CA1 2152/4885CA2 660/4885CA7 1055/4885
US-20200361893-A1 POLYSUBSTITUTED BENZENE, PREPARATION METHOD THEREOF, AND METHOD OF USING THE SAME CBR1, CBR3, C1S CA1 2848/4885CA2 2899/4885CA7 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.