SCHEMBL31117023

SCHEMBL31117023

CC(=O)CCC(F)=C(F)F

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
LMNA P02545 2/20 0.48
SLC15A2 Q16348 1/20 0.48
TDP1 Q9NUW8 1/20 0.35
ACHE P22303 1/20 0.35
PAOX Q6QHF9 1/20 0.35
TRPA1 O75762 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28060459 0.77 ALDH1A1 (1.00) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL10001 0.77
SCHEMBL14415269 0.77 ALDH1A1 (0.59) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL10429017 0.74 ALDH1A1 (0.44) ALDH1A1LMNATDP1SMN1; SMN2CHRM1
SCHEMBL27722569 0.73
SCHEMBL6801343 0.73
SCHEMBL11615492 0.73
SCHEMBL6669487 0.73
SCHEMBL27584016 0.73
SCHEMBL866311 0.73 LMNA (0.34) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682141-A1 TRICYCLIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2026-01-21 EP disclosed
WO-2024190777-A1 TRICYCLIC COMPOUND 小野薬品工業株式会社 2024-09-19 WO disclosed
WO-2024190780-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR KIDNEY DISEASES CONTAINING TRICYCLIC COMPOUND 小野薬品工業株式会社 2024-09-19 WO disclosed