Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118998 | 0.80 | RECQL (0.52) | RECQLSMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL8357994 | 0.78 | RECQL (0.53) | RECQLSMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL8616007 | 0.77 | MTNR1A (0.53) | RECQLALDH1A1HTT | |
| SCHEMBL5524437 | 0.75 | NR1H2 (0.58) | RECQLSMN1; SMN2POLBALDH1A1MEN1 | |
| SCHEMBL5525817 | 0.73 | MEN1 (0.67) | RECQLSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL31118953 | 0.72 | RECQL (0.49) | RECQLSMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL21045990 | 0.70 | ALDH1A1 (0.57) | RECQLALDH1A1HTTMEN1KMT2A | |
| SCHEMBL25783675 | 0.70 | MEN1 (0.48) | POLBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6551029 | 0.70 | RECQL (0.52) | RECQLSMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL31118993 | 0.70 | PTGDR2 (0.43) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4660184-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING HYDROXAMATES, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024159287-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING HYDROXAMATES, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2024-08-08 | — | — | WO | disclosed |