Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | NQO2 | P16083 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558965 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HTT | |
| SCHEMBL29421589 | 0.80 | LMNA (0.63) | MTNR1AHTR2AMTNR1BNQO2HTR2C | |
| SCHEMBL121145 | 0.80 | LMNA (0.63) | MTNR1AHTR2AMTNR1BNQO2HTR2C | |
| SCHEMBL8357994 | 0.79 | RECQL (0.53) | RECQLALDH1A1HTT | |
| SCHEMBL31118998 | 0.78 | RECQL (0.52) | RECQLALDH1A1HTT | |
| SCHEMBL31118985 | 0.77 | RECQL (0.48) | RECQLALDH1A1HTT | |
| SCHEMBL5524437 | 0.76 | NR1H2 (0.58) | RECQLALDH1A1 | |
| SCHEMBL12013659 | 0.75 | HTR2A (0.65) | MTNR1AHTR2AMTNR1BNQO2HTR2C | |
| SCHEMBL3248269 | 0.74 | HTR2A (0.54) | MTNR1AHTR2AMTNR1BNQO2HTR2C | |
| SCHEMBL8639904 | 0.74 | MTNR1A (0.64) | MTNR1AHTR2AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709371-B1 | O-arylmethyl N-(thio)acyl hydroxylamines as ligands for the melatonine receptors, their processes of preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1998-05-06 | — | — | EP | disclosed |
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |
| EP-0709371-A1 | O-arylmethyl N-(thio)acyl hydroxylamines as ligands for the melatonine receptors, their processes of preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |