Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937524 | 0.86 | ACE (0.44) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL31120568 | 0.82 | ACE (0.40) | ACEMMP13KDM4EALDH1A1MAPK1 | |
| SCHEMBL30937651 | 0.81 | ACE (0.53) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937681 | 0.78 | ACE (0.42) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937732 | 0.78 | ACE (0.44) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937672 | 0.76 | ACE (0.41) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937538 | 0.72 | PER2 (0.45) | KMT2AKDM4EMEN1ALDH1A1RAB9A | |
| SCHEMBL30937518 | 0.71 | DPP4 (0.38) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937727 | 0.71 | ACE (0.35) | ACEMMP13KMT2AKDM4EMEN1 | |
| SCHEMBL30937691 | 0.71 | ACE (0.43) | ACEMMP13KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024206347-A1 | FUSED THIADIAZINE DIOXIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |