Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 8/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024590 | 0.88 | ACE (0.54) | CTSCACEACE2 | |
| SCHEMBL29580104 | 0.88 | CALCRL (0.56) | PSMB9CALCRLRENCMA1 | |
| SCHEMBL31122219 | 0.87 | CALCRL (0.49) | PSMB9CALCRLACE | |
| SCHEMBL30434146 | 0.84 | REN (0.49) | PSMB9CALCRLCTSCACEREN | |
| SCHEMBL10777748 | 0.84 | REN (0.51) | ACEACE2REN | |
| SCHEMBL10791014 | 0.84 | CTSC (0.60) | CALCRLCTSCACEREN | |
| SCHEMBL10790985 | 0.84 | CTSC (0.60) | CALCRLCTSCACEREN | |
| SCHEMBL29580266 | 0.83 | CMA1 (0.54) | CTSCRENCMA1 | |
| SCHEMBL30829334 | 0.82 | CTSC (0.51) | CTSCACEACE2RENCMA1 | |
| SCHEMBL30325318 | 0.80 | CTSC (0.47) | CALCRLCTSCREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118403146-A | Application of polypeptide PEP-Z-2 in preparation of medicines for treating kidney fibrosis | 中国医学科学院药物研究所 | 2024-07-30 | — | — | CN | disclosed |