SCHEMBL3112337

SCHEMBL3112337

N[C@@H](C(=O)O)C(I)c1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
NR1I2 O75469 1/20 0.44
PTGS1 P23219 1/20 0.44
ADRA1A P35348 1/20 0.44
LMNA P02545 1/20 0.44
BLM P54132 1/20 0.44
SRC P12931 1/20 0.44
SLC7A5 Q01650 1/20 0.44
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
CYP2C9 P11712 4/20 0.40
CYP2C19 P33261 3/20 0.40
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 2/20 0.40
ALDH1A1 P00352 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL189878 1.00 TDP1 (0.44) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL28688103 1.00 TDP1 (0.44) TDP1NR1I2PTGS1ADRA1ALMNA
Iodide SCHEMBL27294834 0.98 TDP1 (0.43) TDP1NR1I2PTGS1ADRA1ALMNA
Methane SCHEMBL20292606 0.98 TDP1 (0.43) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL14935915 0.83 CYP2D6 (0.48) LMNASRCKMT2AMEN1CYP2C9
SCHEMBL2939473 0.83 CYP2D6 (0.48) LMNASRCKMT2AMEN1CYP2C9
Methane SCHEMBL5182249 0.82 CYP2D6 (0.46) LMNASRCKMT2AMEN1CYP2C9
Methane SCHEMBL5182658 0.82 CYP2D6 (0.46) LMNASRCKMT2AMEN1CYP2C9
SCHEMBL3666840 0.79 SRC (0.47) TDP1PTGS1ADRA1ALMNASRC
SCHEMBL6046193 0.79 TDP1 (0.47) TDP1NR1I2PTGS1ADRA1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4590345-A2 HIGH-PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF Nuclidium AG (CH) 2025-07-30 EP claimed
WO-2024064969-A2 HIGH-PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-03-28 WO claimed
US-20260137818-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2026-05-21 US disclosed
US-12622984-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof NUCLIDIUM AG (CH) 2026-05-12 US disclosed
US-12527885-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof NUCLIDIUM AG (CH) 2026-01-20 US disclosed
EP-4590345-A2 HIGH-PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF Nuclidium AG (CH) 2025-07-30 EP disclosed
US-20240189460-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-06-13 US disclosed
US-20240173441-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-05-30 US disclosed
US-20240173440-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-05-30 US disclosed
WO-2024064969-A2 HIGH-PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-03-28 WO disclosed
US-20240067599-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ABX ADVANCED BIOCHEMICAL COMPOUNDS - BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) 2024-02-29 US disclosed
EP-1161449-B1 MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARM INC (US) 2007-07-04 EP disclosed
CN-1279053-C Modulators for beta-amyloid peptide aggregation comprising D-amino acids PRAECIS PHARM INC (US) 2006-10-11 CN disclosed
US-20050137128-A1 Modulators of ß-amyloid peptide aggregation PRAECIS PHARMACEUTICALS, INC. (US) 2005-06-23 US disclosed
US-6831066-B2 Amyloid precursor proteins with improved bioavailability; for treament of Alzheimer's disease PRAECIS PHARMACEUTICALS INCORPORATED 2004-12-14 US disclosed
US-6610658-B1 Oligopeptides used as time release agents, for transporting drugs across the blood-brain barrier, medical diagnosis and therapy for amyloidosis such as Alzheimer's disease PRAECIS PHARMACEUTICALS INC. 2003-08-26 US disclosed
CN-1362967-A D-amino acid-containing regulator of beta-amyloid peptide aggregation PRAECIS PHARM INC (US) 2002-08-07 CN disclosed
WO-2000052048-A9 MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARM INC (US) 2002-04-11 WO disclosed
EP-1161449-A1 MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS Praecis Pharmaceuticals Incorporated (US) 2001-12-12 EP disclosed
WO-2000052048-A1 MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARMACEUTICALS INCORPORATED (US) 2000-09-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527885-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof SSTR1, PSMA1, KLK3 TDP1 2926/4885NR1I2 1772/4885PTGS1 2635/4885
US-20240173441-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 TDP1 3119/4885NR1I2 2430/4885PTGS1 4468/4885
US-20260137818-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF FAP, SSTR1, PSMA1 TDP1 1379/4885NR1I2 3584/4885PTGS1 1650/4885
US-20240173440-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 TDP1 3119/4885NR1I2 2430/4885PTGS1 4468/4885
US-20240067599-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ALK, ALKBH3, INSR TDP1 3729/4885NR1I2 2633/4885PTGS1 3707/4885
US-20050137128-A1 Modulators of ß-amyloid peptide aggregation APP, IAPP, BACE1 TDP1 2532/4885NR1I2 1826/4885PTGS1 4578/4885
US-20240189460-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 TDP1 3119/4885NR1I2 2430/4885PTGS1 4468/4885
US-12622984-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof SSTR2, SSTR1, SSTR3 TDP1 3699/4885NR1I2 722/4885PTGS1 3582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.