SCHEMBL189878

SCHEMBL189878

N[C@H](C(=O)O)C(I)c1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
NR1I2 O75469 1/20 0.44
PTGS1 P23219 1/20 0.44
ADRA1A P35348 1/20 0.44
LMNA P02545 1/20 0.44
BLM P54132 1/20 0.44
SRC P12931 1/20 0.44
SLC7A5 Q01650 1/20 0.44
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
CYP2C9 P11712 4/20 0.40
CYP2C19 P33261 3/20 0.40
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 2/20 0.40
ALDH1A1 P00352 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688103 1.00 TDP1 (0.44) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL3112337 1.00 TDP1 (0.44) TDP1NR1I2PTGS1ADRA1ALMNA
Iodide SCHEMBL27294834 0.98 TDP1 (0.43) TDP1NR1I2PTGS1ADRA1ALMNA
Methane SCHEMBL20292606 0.98 TDP1 (0.43) TDP1NR1I2PTGS1ADRA1ALMNA
SCHEMBL14935915 0.83 CYP2D6 (0.48) LMNASRCKMT2AMEN1CYP2C9
SCHEMBL2939473 0.83 CYP2D6 (0.48) LMNASRCKMT2AMEN1CYP2C9
Methane SCHEMBL5182249 0.82 CYP2D6 (0.46) LMNASRCKMT2AMEN1CYP2C9
Methane SCHEMBL5182658 0.82 CYP2D6 (0.46) LMNASRCKMT2AMEN1CYP2C9
SCHEMBL3666840 0.79 SRC (0.47) TDP1PTGS1ADRA1ALMNASRC
SCHEMBL6046193 0.79 TDP1 (0.47) TDP1NR1I2PTGS1ADRA1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 US claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
US-20250243472-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-07-31 US claimed
CN-119574735-A Method for detecting organic iodine in seaweed 益盐堂(应城)健康盐制盐有限公司 2025-03-07 CN claimed
CN-119104644-A Analysis method for determining organic iodine in seaweed iodized salt by using amino acid analyzer 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2024-12-10 CN claimed
US-20240400672-A1 NOVEL MONOCLONAL ANTIBODIES DIRECTED AGAINST L-THYROXINE AND DIAGNOSTIC USES THEREOF F. HOFFMANN-LA ROCHE AG (CH) 2024-12-05 US claimed
CN-118688315-A Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds 复旦大学 2024-09-24 CN claimed
EP-4430074-A1 NOVEL MONOCLONAL ANTIBODIES DIRECTED AGAINST L-THYROXINE AND DIAGNOSTIC USES THEREOF F. Hoffmann-La Roche AG (CH) 2024-09-18 EP claimed
WO-2024138422-A1 PIN DOMAIN, HELICASE CONTAINING SAME, PREPARATION METHOD FOR PIN DOMAIN, AND USE OF PIN DOMAIN 深圳华大生命科学研究院 2024-07-04 WO claimed
WO-2024138632-A1 HELICASE, PREPARATION METHOD THEREFOR AND USE THEREOF IN SEQUENCING 深圳华大生命科学研究院 2024-07-04 WO claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
EP-0672148-A1 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM Biosource Technologies, Inc. (US) 1995-09-20 EP claimed
US-5340734-A In vitro biosynthesis the melanins in presence of a substrate consisting of tyrosine binding single amino acid, a dipeptide or an oligopeptide BIOSOURCE GENETICS CORPORATION (US) 1994-08-23 US claimed
WO-1994012644-A2 METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM BIOSOURCE GENETICS CORPORATION (US) 1994-06-09 WO claimed
EP-0547065-A4 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS 1993-09-15 EP claimed
EP-0547065-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS Biosource Technologies, Inc. (US) 1993-06-23 EP claimed
WO-1992000373-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS BIOSOURCE GENETICS CORPORATION (CA) 1992-01-09 WO claimed
EP-0103784-B1 CATALYZED COLORIMETRIC AND FLUOROMETRIC SUBSTRATES FOR PEROXIDASE ENZYME DETERMINATIONS ENZYME TECHNOLOGY COMPANY (US) 1988-01-07 EP claimed
US-4521511-A SUBSTITUTED PHENOLS AS ACCELERATOR ENZYME TECHNOLOGY COMPANY (US) 1985-06-04 US claimed
EP-0103784-A2 Catalyzed colorimetric and fluorometric substrates for peroxidase enzyme determinations ENZYME TECHNOLOGY COMPANY (US) 1984-03-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM NPPA, MACF1, IGF1R TDP1 3434/4885NR1I2 3023/4885PTGS1 2222/4885
US-20240400672-A1 NOVEL MONOCLONAL ANTIBODIES DIRECTED AGAINST L-THYROXINE AND DIAGNOSTIC USES THEREOF IGLV6-57, THRB, TSHR TDP1 3296/4885NR1I2 4071/4885PTGS1 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.