Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.34 |
| ▸ | ADK | P55263 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21678732 | 0.86 | DGAT1 (0.33) | DGAT1ADKMEN1NR2F2KMT2A | |
| SCHEMBL20555312 | 0.85 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL21678638 | 0.84 | ADK (0.33) | DGAT1ADK | |
| SCHEMBL21678768 | 0.83 | ADK (0.36) | DGAT1ADK | |
| SCHEMBL21678372 | 0.82 | DGAT1 (0.33) | DGAT1ADK | |
| SCHEMBL31070110 | 0.82 | DGAT1 (0.33) | DGAT1ADK | |
| SCHEMBL16259168 | 0.82 | ADK (0.40) | DGAT1ADKMEN1NR2F2KMT2A | |
| SCHEMBL31340598 | 0.82 | ADK (0.40) | DGAT1ADKMEN1NR2F2KMT2A | |
| SCHEMBL21801375 | 0.81 | RET (0.52) | RET | |
| SCHEMBL27096809 | 0.81 | GPR119 (0.37) | DGAT1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |