Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30560776 | 1.00 | L3MBTL1 (0.32) | L3MBTL1HRH3SIGMAR1HTR7 | |
| SCHEMBL31124238 | 1.00 | L3MBTL1 (0.32) | L3MBTL1HRH3SIGMAR1HTR7 | |
| SCHEMBL31124157 | 0.90 | SLC6A1 (0.35) | HRH3 | |
| SCHEMBL2560134 | 0.82 | HRH2 (0.38) | HRH3SIGMAR1 | |
| SCHEMBL2385027 | 0.79 | GNAI3 (0.43) | L3MBTL1HRH3 | |
| SCHEMBL3928132 | 0.79 | GNAI3 (0.43) | L3MBTL1HRH3 | |
| SCHEMBL25188572 | 0.78 | — | — | |
| SCHEMBL6277605 | 0.78 | — | — | |
| SCHEMBL2553857 | 0.78 | PDCD1 (0.40) | HRH3 | |
| SCHEMBL31124137 | 0.78 | CARM1 (0.38) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | claimed |
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |