Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676638 | 1.00 | MDM2 (0.34) | MDM2NR4A1POLBESR2MAOA | |
| SCHEMBL5942495 | 0.92 | MDM2 (0.35) | MDM2NR4A1POLBESR2MAOA | |
| SCHEMBL5942565 | 0.91 | MAOA (0.31) | MDM2NR4A1MAOARORCPDE5A | |
| SCHEMBL677216 | 0.90 | MDM2 (0.34) | MDM2NR4A1POLBESR2MAOA | |
| SCHEMBL31124325 | 0.90 | MDM2 (0.34) | MDM2NR4A1POLBESR2MAOA | |
| SCHEMBL6246609 | 0.88 | MDM2 (0.33) | MDM2NR4A1POLBESR2 | |
| SCHEMBL6246269 | 0.88 | RORC (0.31) | RORC | |
| SCHEMBL677643 | 0.88 | ULK1 (0.31) | POLB | |
| SCHEMBL5942267 | 0.87 | MDM2 (0.32) | MDM2NR4A1AURKAKDRAURKB | |
| SCHEMBL6246188 | 0.87 | MDM2 (0.35) | MDM2NR4A1POLBESR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441967-B | Preparation method of methoxybenzene cry bacterial intermediate | 南北兄弟药业投资有限公司 | 2024-10-29 | — | — | CN | disclosed |