Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728162 | 0.87 | POLB (0.55) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL5585931 | 0.81 | GPR6 (0.56) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL11034109 | 0.78 | NOS1 (0.52) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL912170 | 0.74 | ALDH1A1 (0.40) | POLBALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11358451 | 0.73 | NOS1 (0.60) | ALDH1A1GAAMAPTPKMKDM4E | |
| SCHEMBL11647947 | 0.71 | CYP2C9 (0.57) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL10969223 | 0.71 | ITGB1 (0.35) | POLBALDH1A1GAA | |
| SCHEMBL27552925 | 0.71 | HTT (0.59) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3346307 | 0.71 | KMT2A (0.54) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL656655 | 0.70 | POLB (0.97) | POLBALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118655238-A | Method for detecting content of 4-ethyl-2, 3-dioxypiperazine formyl chloride and related substances | 山东鲁抗医药股份有限公司 | 2024-09-17 | — | — | CN | disclosed |