Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670946 | 0.80 | CSF1R (0.31) | — | |
| SCHEMBL31126645 | 0.80 | CSF1R (0.31) | — | |
| SCHEMBL31126648 | 0.80 | MAPT (0.36) | MAPTPOLBBMP1ALDH1A1LMNA | |
| SCHEMBL16794693 | 0.76 | MAPT (0.42) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16794676 | 0.75 | PDE1B (0.40) | ALDH1A1SMN1; SMN2HTTRAB9AKMT2A | |
| SCHEMBL18161034 | 0.75 | PDE1B (0.41) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL16812355 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL16812352 | 0.75 | PDE1B (0.38) | MAPTPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL24263381 | 0.74 | PDE1B (0.39) | ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL16812486 | 0.73 | NPC1 (0.40) | MAPTPOLBALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692096-A1 | MACROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Prime Gene Therapeutics Co., Ltd. (CN) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024199479-A1 | MACROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2024-10-03 | — | — | WO | disclosed |