Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126644 | 0.81 | TUBB4A (0.34) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL32670945 | 0.81 | TUBB4A (0.34) | POLBALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL31126646 | 0.80 | MAPT (0.38) | MAPTPOLBALDH1A1SMN1; SMN2BMP1 | |
| SCHEMBL23327454 | 0.77 | MAPT (0.42) | MAPTPOLBALDH1A1BMP1LMNA | |
| SCHEMBL26098304 | 0.76 | PTPN1 (0.49) | MAPTPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL21811192 | 0.75 | KDM4E (0.44) | MAPTPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23327622 | 0.72 | MAPT (0.39) | MAPTPOLBALDH1A1BMP1LMNA | |
| SCHEMBL31245696 | 0.70 | KDM4E (0.42) | MAPTPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20689640 | 0.69 | KDM4E (0.46) | MAPTPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL29344675 | 0.68 | ALDH1A1 (0.34) | POLBALDH1A1SMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692096-A1 | MACROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Prime Gene Therapeutics Co., Ltd. (CN) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024199479-A1 | MACROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2024-10-03 | — | — | WO | disclosed |