Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128612 | 0.88 | NOTUM (0.37) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128562 | 0.79 | S1PR1 (0.33) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128534 | 0.79 | S1PR1 (0.38) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL31128494 | 0.78 | KDM4E (0.39) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128514 | 0.76 | MAPT (0.41) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128602 | 0.75 | AR (0.44) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL31128615 | 0.74 | KDM4E (0.32) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128539 | 0.73 | PAX8 (0.46) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL31128519 | 0.73 | PAX8 (0.46) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL15646608 | 0.67 | KDM4E (0.42) | ALDH1A1KDM4ES1PR1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173343-A1 | COMPOUNDS TARGETING HYDROXYSTEROID 17-BETA DEHYDROGENASE (HSD17B) AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |