Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128596 | 0.87 | NOTUM (0.41) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL31128495 | 0.78 | MAPT (0.33) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL31128602 | 0.77 | AR (0.44) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL31128547 | 0.75 | THRB (0.49) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL31128570 | 0.73 | DCTPP1 (0.37) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL31128590 | 0.73 | RXFP1 (0.41) | KDM4ETDP1MAPTLMNARXFP1 | |
| SCHEMBL31128534 | 0.71 | S1PR1 (0.38) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL10373598 | 0.69 | — | — | |
| SCHEMBL7095254 | 0.68 | PGR (0.55) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29662946 | 0.68 | PGR (0.55) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173343-A1 | COMPOUNDS TARGETING HYDROXYSTEROID 17-BETA DEHYDROGENASE (HSD17B) AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |