Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128567 | 0.87 | NOTUM (0.49) | ARPGRS1PR1XDHKDM4E | |
| SCHEMBL31128534 | 0.84 | S1PR1 (0.38) | S1PR1XDHKDM4EALDH1A1TDP1 | |
| SCHEMBL31128539 | 0.80 | PAX8 (0.46) | S1PR1KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL31128519 | 0.80 | PAX8 (0.46) | S1PR1KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL31128494 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL2765509 | 0.76 | CYP3A4 (0.45) | S1PR1KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL31128495 | 0.75 | MAPT (0.33) | S1PR1XDHKDM4EALDH1A1TDP1 | |
| SCHEMBL31128590 | 0.73 | RXFP1 (0.41) | PGRS1PR1KDM4ETDP1MAPT | |
| SCHEMBL31128616 | 0.71 | S1PR1 (0.40) | S1PR1KDM4EALDH1A1TDP1MAPT | |
| SCHEMBL31128525 | 0.71 | NOTUM (0.43) | S1PR1XDHKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173343-A1 | COMPOUNDS TARGETING HYDROXYSTEROID 17-BETA DEHYDROGENASE (HSD17B) AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |