Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15437039 | 0.82 | TP53 (0.72) | THRBMAPTTP53LMNARXFP1 | |
| SCHEMBL15468398 | 0.79 | MAPT (0.68) | THRBMAPTTP53ACRALDH1A1 | |
| SCHEMBL31128646 | 0.77 | MAPK1 (0.46) | THRBMAPTTP53LMNAACR | |
| SCHEMBL31128598 | 0.77 | NOTUM (0.46) | THRBRXFP1 | |
| SCHEMBL31128547 | 0.76 | THRB (0.49) | THRBMAPTTP53LMNAALDH1A1 | |
| SCHEMBL2765109 | 0.75 | MAPK1 (0.54) | THRBMAPTTP53ACRALDH1A1 | |
| SCHEMBL31128590 | 0.74 | RXFP1 (0.41) | THRBMAPTLMNARXFP1 | |
| SCHEMBL15464385 | 0.72 | TP53 (0.51) | THRBMAPTTP53LMNAACR | |
| SCHEMBL14167735 | 0.72 | TP53 (0.51) | THRBMAPTTP53LMNAACR | |
| SCHEMBL21523720 | 0.72 | MAPK1 (0.76) | THRBMAPTTP53RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173343-A1 | COMPOUNDS TARGETING HYDROXYSTEROID 17-BETA DEHYDROGENASE (HSD17B) AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |