Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969435 | 0.78 | SMN1; SMN2 (0.44) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL158909 | 0.78 | ATM (0.39) | METAP2MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL3751343 | 0.78 | ASIC3 (0.44) | METAP2 | |
| SCHEMBL4331812 | 0.76 | LMNA (0.43) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL22080186 | 0.74 | TP53 (0.44) | METAP2 | |
| SCHEMBL10866586 | 0.74 | MAPT (0.44) | ADORA2BAPP | |
| SCHEMBL13881958 | 0.74 | NOTUM (0.44) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL1233272 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL12131262 | 0.72 | — | — | |
| SCHEMBL12130494 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655301-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | Epirium Bio Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158931-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO INC. (US) | 2024-08-02 | — | — | WO | disclosed |