Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794405 | 1.00 | GFER (0.39) | GFERHDAC1CAPN1HDAC6AR | |
| SCHEMBL3123810 | 0.91 | LMNA (0.42) | GFERHDAC1CAPN1HDAC6DPP4 | |
| SCHEMBL3021565 | 0.87 | GFER (0.34) | GFERCAPN1HDAC6ARDPP4 | |
| SCHEMBL3021562 | 0.87 | GFER (0.34) | GFERCAPN1HDAC6ARDPP4 | |
| SCHEMBL3123749 | 0.84 | GFER (0.35) | GFERDPP4PLA2G10PLA2G5RIPK1 | |
| SCHEMBL3123755 | 0.84 | GFER (0.35) | GFERDPP4PLA2G10PLA2G5RIPK1 | |
| SCHEMBL3022438 | 0.84 | GFER (0.35) | GFERCAPN1HDAC6ARDPP4 | |
| SCHEMBL3022436 | 0.84 | GFER (0.35) | GFERCAPN1HDAC6ARDPP4 | |
| SCHEMBL3118211 | 0.84 | MAPT (0.41) | HDAC1MEN1KMT2A | |
| SCHEMBL3112948 | 0.84 | GFER (0.35) | GFERCAPN1HDAC6CES2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190794-A1 | Herbicidally Active Composition | BASF SE (DE) | 2010-07-29 | — | — | US | claimed |
| US-20100190794-A1 | Herbicidally Active Composition | BASF SE (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2061770-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL ACTION | BASF SE (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009000757-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL ACTION | BASF SE (DE) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | CBR3, CBR1, CNPY2 | GFER 739/4885HDAC1 937/4885CAPN1 355/4885 |
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | PRXL2A, CBR1, CBR3 | GFER 332/4885HDAC1 1015/4885CAPN1 1183/4885 |
| US-20100190794-A1 | Herbicidally Active Composition | ECI1, ACLY, SQOR | GFER 47/4885HDAC1 3695/4885CAPN1 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.