Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28237818 | 0.77 | DDB1 (0.48) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL20215514 | 0.76 | ALKBH5 (0.46) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL13106236 | 0.73 | SSTR4 (0.40) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL13106346 | 0.73 | LMNA (0.43) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL13106244 | 0.73 | SSTR4 (0.40) | ADORA2AADORA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL20257297 | 0.70 | SLC9A1 (0.44) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL17616526 | 0.70 | ADORA2A (0.37) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL13202677 | 0.70 | KDM4E (0.49) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL29957096 | 0.70 | ADORA2A (0.37) | ADORA2AADORA2BMAPTLMNAMEN1 | |
| SCHEMBL28138780 | 0.70 | PIM3 (0.44) | LMNAL3MBTL1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4442318-A2 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2024-10-09 | — | — | EP | disclosed |