Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105176 | 0.85 | RAB9A (0.43) | TRPV1LMNAPKMNAMPTHTT | |
| SCHEMBL113050 | 0.83 | TRPV1 (0.44) | TRPV1LMNAHTTTYK2KDM4E | |
| SCHEMBL111886 | 0.81 | ADRA1D (0.44) | TRPV1HTTTYK2KDM4ESMN1; SMN2 | |
| SCHEMBL3105119 | 0.80 | TRPV1 (0.50) | TRPV1HTTTYK2KDM4ESMN1; SMN2 | |
| SCHEMBL111684 | 0.79 | HDAC1 (0.41) | TRPV1LMNAHTTTYK2JAK2 | |
| SCHEMBL3101690 | 0.78 | HSD17B10 (0.55) | TRPV1LMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL163235 | 0.77 | HSD17B10 (0.45) | TRPV1LMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL111857 | 0.75 | TRPV1 (0.47) | TRPV1HTTTYK2KDM4ESMN1; SMN2 | |
| SCHEMBL162320 | 0.75 | CXCR3 (0.51) | TRPV1LMNAHTTTYK2SMN1; SMN2 | |
| SCHEMBL111833 | 0.73 | CXCR3 (0.61) | TRPV1LMNANAMPTTYK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362249-B2 | CXCR3 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20100273781-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273781-A1 | CXCR3 RECEPTOR ANTAGONISTS | CXCR3, CXCR1, CXCR2 | TRPV1 332/4885ITGB1 326/4885ITGAV 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.