Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL1988246 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRHTTMEN1GAA | |
| Ether SCHEMBL368206 | 0.90 | — | — | |
| Dioxane SCHEMBL3113374 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRHTTMEN1GAA | |
| Ether SCHEMBL10539362 | 0.87 | TTR (0.43) | ALDH1A1TSHRHTTMEN1GAA | |
| Ether SCHEMBL8643412 | 0.87 | — | — | |
| Dioxane SCHEMBL1559719 | 0.87 | TTR (0.43) | ALDH1A1TSHRHTTMEN1GAA | |
| Ether SCHEMBL233512 | 0.87 | TTR (0.43) | ALDH1A1TSHRHTTMEN1GAA | |
| Tetrahydrofuran SCHEMBL6282154 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TSHRHTTL3MBTL1RECQL | |
| Ether SCHEMBL12988654 | 0.84 | TSHR (0.34) | ALDH1A1TSHRMEN1GAAKMT2A | |
| Ether SCHEMBL28468837 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112029591-A | Nano-emulsion cleaning agent and preparation method thereof | 中国船舶重工集团公司第七一八研究所 | 2020-12-04 | — | — | CN | claimed |
| CN-110306358-A | A kind of processing method of real silk fabric natural dye dying | 苏州虹锦生态纺织科技有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-108359540-A | Virtual unit screen cleaning agent and preparation method thereof | 芜湖易法网络科技有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-87100343-A | The manufacture method of fusible pattern plaster mold and coating | — | 1988-04-06 | — | — | CN | claimed |
| CN-112029591-A | Nano-emulsion cleaning agent and preparation method thereof | 中国船舶重工集团公司第七一八研究所 | 2020-12-04 | — | — | CN | disclosed |
| CN-110512437-A | A kind of tencel, fiber crops, cotton intertexture weft elastic fabric dyeing and finishing technology | JIAXING LIHUA PRINTING AND DYEING CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-110306358-A | A kind of processing method of real silk fabric natural dye dying | 苏州虹锦生态纺织科技有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110002692-A | A kind of Zero-discharge treating process of industry cleaning link waste water | 南京霄祥工程技术有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109371434-A | A kind of neutrality nickel plating solution and neutral nickel plating technology | 江门市德商科佐科技实业有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109251583-A | A kind of woven bag plastics deinking agent | 河南海利未来科技有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-106234408-B | Bactericidal composition and its application | 四川利尔作物科学有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108485833-A | A kind of glass anti-pollution cleaning solution and preparation method thereof | 安徽凤阳淮河玻璃有限公司 | 2018-09-04 | — | — | CN | disclosed |
| WO-1999055528-A1 | HEAT-SHRINKABLE MULTILAYER FILM | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-11-04 | — | — | WO | disclosed |
| US-5362483-A | Flavoring, fragrance, skin texturizing and deodorant materials and method of making same | MORGAN FOOD PRODUCTS, INC. (US) | 1994-11-08 | — | — | US | disclosed |
| US-5328684-A | Flavoring, fragance, skin texturizing and deodorant materials and method of making same | MORGAN FOOD PRODUCTS, INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5322696-A | Flavoring, fragrance, skin texturizing and deodorant materials and method of making same | MORGAN FOOD PRODUCTS, INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5223260-A | FLAVORING, FRAGRANCE, SKIN TEXTURIZING AND DEODORANT MATERIALS AND METHOD OF MAKING SAME | MORGAN FOOD PRODUCTS, INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0380965-A2 | Flavoring, fragrance, skin texturizing and deodorant materials and method of making same | MORGAN FOOD PRODUCTS, INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| CN-87100343-A | The manufacture method of fusible pattern plaster mold and coating | — | 1988-04-06 | — | — | CN | disclosed |
| US-4264457-A | MIXTURES WITH ANIONIC AND NONIONIC SURFACTANTS | DESOTO, INC. (US) | 1981-04-28 | — | — | US | disclosed |