SCHEMBL31138405

SCHEMBL31138405

Cn1cc2nc(Cl)nc(OCc3ccc(-c4nc(C(F)(F)F)cn4C)cc3)c2n1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575980 0.89 USP1 (0.42) USP1
SCHEMBL31155876 0.85 USP1 (0.44) USP1
SCHEMBL31254865 0.83 USP1 (0.47) USP1
SCHEMBL31537682 0.83 USP1 (0.45) USP1
SCHEMBL31138478 0.83 USP1 (0.44) USP1
SCHEMBL31254665 0.83 USP1 (0.46) USP1
SCHEMBL31138403 0.82 USP1 (0.42) USP1
SCHEMBL31537623 0.81 USP1 (0.44) USP1
SCHEMBL31254808 0.81 USP1 (0.47) USP1
SCHEMBL31155857 0.81 USP1 (0.47) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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