Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31537603 | 0.90 | SYK (0.38) | USP1 | |
| SCHEMBL31537724 | 0.86 | USP1 (0.40) | USP1 | |
| SCHEMBL31537682 | 0.86 | USP1 (0.45) | USP1 | |
| SCHEMBL31138405 | 0.85 | USP1 (0.42) | USP1 | |
| SCHEMBL31537656 | 0.84 | USP1 (0.46) | USP1 | |
| SCHEMBL31254865 | 0.83 | USP1 (0.47) | USP1 | |
| SCHEMBL30462043 | 0.82 | USP1 (0.46) | USP1 | |
| SCHEMBL31254665 | 0.82 | USP1 (0.46) | USP1 | |
| SCHEMBL31138403 | 0.81 | USP1 (0.42) | USP1 | |
| SCHEMBL31537623 | 0.80 | USP1 (0.44) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096494-A1 | UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |