SCHEMBL31138403

SCHEMBL31138403

Cn1cc(C(F)(F)F)nc1-c1ccc(COc2nc(Cl)nc3ccoc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31155858 0.88 USP1 (0.42) USP1
SCHEMBL31138583 0.86 USP1 (0.41) USP1
SCHEMBL31155899 0.85 USP1 (0.41) USP1
SCHEMBL31138784 0.85 USP1 (0.41) USP1
SCHEMBL31155907 0.85 USP1 (0.38) USP1
SCHEMBL31138559 0.84 HDAC1 (0.33) USP1
SCHEMBL31537682 0.84 USP1 (0.45) USP1
SCHEMBL31254865 0.83 USP1 (0.47) USP1
SCHEMBL31254665 0.82 USP1 (0.46) USP1
SCHEMBL31138405 0.82 USP1 (0.42) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096487-A1 UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
WO-2024208292-A1 UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2024-10-10 — — WO disclosed
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