Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.65 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300737 | 1.00 | SMARCA2 (0.65) | SMARCA2SMARCA4ARMALT1ALDH1A1 | |
| SCHEMBL9599834 | 0.84 | SMARCA2 (0.86) | SMARCA2SMARCA4MALT1ALDH1A1CNR1 | |
| SCHEMBL11380322 | 0.84 | KDR (0.57) | ARALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL31140004 | 0.84 | SMARCA2 (0.69) | SMARCA2SMARCA4ALDH1A1CNR1MEN1 | |
| SCHEMBL25301796 | 0.84 | SMARCA2 (0.69) | SMARCA2SMARCA4ALDH1A1CNR1MEN1 | |
| SCHEMBL22125487 | 0.81 | SMARCA2 (0.67) | SMARCA2SMARCA4MALT1ALDH1A1CNR1 | |
| SCHEMBL25832379 | 0.81 | SMARCA2 (0.66) | SMARCA2SMARCA4MALT1CNR1MEN1 | |
| SCHEMBL17804195 | 0.80 | SMARCA2 (0.64) | SMARCA2SMARCA4ARMALT1SMN1; SMN2 | |
| SCHEMBL29556246 | 0.80 | SMARCA2 (0.60) | SMARCA2SMARCA4MALT1ALDH1A1CNR1 | |
| SCHEMBL22125195 | 0.79 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118695863-A | Targeting SWI/SNF-related matrix-associated actin-dependent chromatin regulatory factor subfamily A member 4 (SMARCA 4) | 丹娜-法伯癌症研究院 | 2024-09-24 | — | — | CN | disclosed |