Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.69 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.69 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301796 | 1.00 | SMARCA2 (0.69) | SMARCA2SMARCA4KDRCNR1S1PR2 | |
| SCHEMBL9599834 | 0.88 | SMARCA2 (0.86) | SMARCA2SMARCA4CNR1S1PR2ALDH1A1 | |
| SCHEMBL25832379 | 0.88 | SMARCA2 (0.66) | SMARCA2SMARCA4KDRCNR1S1PR2 | |
| SCHEMBL119685 | 0.84 | SMARCA2 (0.79) | SMARCA2SMARCA4KDRCNR1MAPT | |
| SCHEMBL31139994 | 0.84 | SMARCA2 (0.65) | SMARCA2SMARCA4KDRCNR1S1PR2 | |
| SCHEMBL25300737 | 0.84 | SMARCA2 (0.65) | SMARCA2SMARCA4KDRCNR1S1PR2 | |
| SCHEMBL27968802 | 0.83 | SMARCA2 (0.72) | SMARCA2SMARCA4CNR1MAPTMEN1 | |
| SCHEMBL22125200 | 0.82 | SMARCA2 (1.00) | SMARCA2SMARCA4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL22125520 | 0.82 | SMARCA2 (0.76) | SMARCA2SMARCA4CNR1S1PR2MAPT | |
| SCHEMBL11047103 | 0.81 | SMARCA2 (0.79) | SMARCA2SMARCA4KDRCNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118695863-A | Targeting SWI/SNF-related matrix-associated actin-dependent chromatin regulatory factor subfamily A member 4 (SMARCA 4) | 丹娜-法伯癌症研究院 | 2024-09-24 | — | — | CN | disclosed |