Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17056237 | 0.87 | PLA2G2A (0.63) | PLA2G2AFAAHTP53TSHR | |
| SCHEMBL31144862 | 0.86 | GPBAR1 (0.46) | MAOBRHOCRHOAALDH1A1HTT | |
| SCHEMBL15977059 | 0.85 | PLA2G2A (0.57) | PLA2G2APARP10GAARAB9ATP53 | |
| SCHEMBL17414620 | 0.85 | PLA2G2A (0.62) | PLA2G2APARP10GAARAB9ATP53 | |
| SCHEMBL31144913 | 0.84 | NOTUM (0.58) | PLA2G2AFAAHRHOCRHOAALDH1A1 | |
| SCHEMBL18758579 | 0.84 | ESR1 (0.52) | PLA2G2AFAAHALDH1A1HTTCYP2D6 | |
| SCHEMBL12331978 | 0.84 | RHOC (0.44) | FAAHMAOBRHOCRHOAALDH1A1 | |
| SCHEMBL16953371 | 0.84 | PLA2G2A (0.43) | PLA2G2AFAAHRHOCRHOAALDH1A1 | |
| SCHEMBL12130271 | 0.83 | AURKA (0.47) | MAOBALDH1A1 | |
| SCHEMBL5086980 | 0.79 | PLA2G2A (0.73) | PLA2G2AGAARAB9ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175804-A1 | NUCLEAR TRANSPORT MODULATORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-08-29 | — | — | WO | disclosed |