Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.30 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043607 | 0.77 | CACNA1B (0.49) | KDM4ETSHRUSP2HTTHSD17B10 | |
| SCHEMBL15046520 | 0.69 | — | — | |
| SCHEMBL12897731 | 0.66 | ALDH1A1 (0.39) | KDM4ETSHRUSP2HTTHSD17B10 | |
| SCHEMBL16039609 | 0.66 | ALDH1A1 (0.39) | KDM4ETSHRUSP2HTTHSD17B10 | |
| SCHEMBL16039625 | 0.65 | USP2 (0.44) | KDM4ETSHRUSP2HTTHSD17B10 | |
| SCHEMBL13528452 | 0.65 | ALDH1A1 (0.53) | KDM4ETSHRUSP2HTTHSD17B10 | |
| SCHEMBL5878378 | 0.64 | ALDH1A1 (0.50) | KDM4ETSHRHTTHSD17B10LMNA | |
| SCHEMBL21430883 | 0.63 | CYP19A1 (0.33) | — | |
| SCHEMBL30131244 | 0.63 | SMN1; SMN2 (0.31) | TSHRUSP2HTTHSD17B10SMN1; SMN2 | |
| SCHEMBL15043600 | 0.63 | KDM4E (0.49) | KDM4EHTTHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816062-B2 | Maleimide-furanyl compounds that can be used in a general method for preparing maleimide-oligonucleotide derivatives | UNIVERSITAT DE BARCELONA (ES) | 2014-08-26 | — | — | US | disclosed |
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025646-A1 | MALEIMIDE‑FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE‑OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | NSUN2, POLL, NT5C3B | KDM4E 729/4885TSHR 2798/4885USP2 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.